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Upir
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General Information
Status

Extant

Distinction

Resurrected and biologically immortal people who feed on blood and do not age past middle age.

Season(s)

123

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Roman feeding on and killing a horse he bought when his hunger was so strong that non living creatures would fail to satisfy his hunger, though it would only grow worse until he would not be able to control it at all

Upir (or opir) are a vampire-like species found in Ukraine and are the natural enemies of werewolves or loup garous. It is quite similar to the Russian/Ukrainian legend of the upyr, the Slavic upior, and the Byelorussian upor. These species start out as seemingly regular humans, though they seem to have a greater tolerance to pain and the ability of mesmerization. Using this power, however, puts a visible strain on their bodies, as they bleed from their noses each time they use it.
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Roman after killing Olivia when rising as a Full upir after cutting his arms and dying

After death by suicide, they become full upir, biologically immortal creatures with enhanced strength, inhuman healing and overall recovery capabilities, as well as inhuman jaw flexibility, toxic enyzmes, and a nearly insatiable, rabid appetite for blood and raw tissue. Naturally, upirs can only become sick or have diseases on the rarest of occasions, such as having a congenital heart defect, which is fatal to them. Once they are in this stage, they will spend months or even years adapting to their new hunger for blood or raw tissue, will often have far less self-control over their hunger and be prone to dangerously aggressive behavior. As they live out their infinite lifespan, they can become changed, usually negatively, by their many experiences over their lives. They usually react on instinct while not thinking straight or not having self-control, especially during dangerous or violent situations.

Either way, these creatures are prone to violent, barbaric, and sometimes murderous behavior whenever they do not have emotional control, a side effect of their more predatorial and aggressive nature. This can make them act brutal and even animalistic in violent situations. Their nature can make them act cruel or inhumane towards others. There are instances in which their emotions can overwhelm them such as when they are sad, but it lasts for a very short time. Poor feeding habits can cause extremely heightening in raw, intense, negative, and aggressive feelings, to the point of the upir becoming dangerously short tempered and even homicidal. They will instinctively react with violence and kill if pushed to their limits. They can continue living or be killed by extreme mutilation dismemberment of the heart, chest, or head. To make certain an upir does not heal from mortal injury, the heart or head is usually removed. They can also be killed by cremation.

Origin and Physiology Edit

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Roman's inhuman jaw strength

According to Folklore full upirs are the spawn of witches and demons and a half-upir is 1/2 human, 1/4 witch, and 1/4 demon.  It can be assumed that they have been around a long time, perhaps since the beginning of time. Scientifically, the upir gene is identified as a heritable retroviral anomaly. This anomaly in the certain genomes is what turns people into upir, but it can only be genetically inherited. It appears that those that are not full upir but are a portion of it or have strong demonic gene in their bloodline will be prone to develop strange
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Roman attacking a guard on instinct with his enhanced jaws, protecting Annie

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Olivia's corpse coming back to life with blue bloodless skin after bleeding out and freezing in the cold, and develops fangs, which were excluded in season 2 and replaced with enhanced jaws and growing mouth

deformities, such as Olivia being born with a short tail like appendage on her back.

Roman and Nadia were born with a thick skin membrane or a caul over

their bodies and normal skin, which was removed, and Shelley having
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Roman bites Dr Arnold Spivak, exposing him to the Upir Toxin.

her misshapen appearance. Though, it seems to have disappeared due to her death or near death at the hand of Thomas Sworn, which may have caused her to die and come back and develop a more human like appearance. Nadia's inhuman blue eyes are her abnormal appearance that signifies her demonic lineage. When Roman
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transformed, he cut his arms and bleed out, causing marks to form on his arms in the place of the wounds and his blood to move on its own up a wall and form a picture of dragon-like wings. Upirs still produce waste and can become pregnant, as upir are still living creatures like
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Roman showing off his stretching mouth

humans and werewolves and with similar traits to them. Roman as a full upir has shown the ability urinate and produce sweat as upir are still living creatures. Pryce stated that he could turn
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upir blood is shown to be darker in color than human blood

an upir into a human through stem cell research by exchanging their tissues and blood for that of a human's and remove the cells with upir genetics to that of humans. This was not demonstrated when Roman went through treatments that required his tissues being stripped from him and his blood drained from him, both being
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Gaber dying of his bite wound from Roman

exchanged for that of humans. Pryce said that enough of these would make him fully human. Since they are different in genotypes from human, their body, specifically at the nervous system, they are incapable of reacting to anaesthesia, rendering it useless in their system. Also, the treatments of purging the upir gene from the upir can cause puss to come from their ears as the body is primed to
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upir suffer from insatiable hunger that eventually consumes them and makes them feral and suffer from hazed senses and overwhelming hunger attacks

purge itself of anything it recognizes as the upir gene. The six treatments must be taken day after day to prime the bodies genetics to accept the human gene and reject the upir gene. If one is missed, especially the last one, then the upir will return to its original state. If the final treatment is missed, the smallest semblance of the upir gene will become infectious in the body, rebinding the gene to the body and causing mutations with unpredictable and possibly catastrophic results. By then, the upir gene will become impossible to eradicate.

Toxin Edit

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The Toxin being extracted from Romans mouth.

These creatures possess a highly degenerative venom in their mouths, which is powerful enough to kill someone of their own kind. The Upir Toxin, also described as Upir Neurotoxin, is shown in the form of excess sinus in the maxilla of the mouth and is created inside a venom gland. While it has little to no effect on humans, it only has negative effects on other upir, as not many humans bitten by an upir in the show have shown any signs of venom. The enzyme can be used for medicinal purposes, breaking down the immune system and weakening an upir's cellular defenses to allow for further treatments. It was used in Olivia's recovery after being killed by Roman, as she could not recover on her own. It was said to have almost killed her in the process. It also caused her to become more human, giving her tissue dystrophy, chemically enhanced emotions and empathy, which was hard to overcome, accelerated aging and decay and even human like vulnerability to cancers, which is a possible side effect of the accelerated aging. Olivia had severe muscular dystrophy after being drained of blood by Roman and being given the Neurotoxin in her treatments, all of which caused her to become so weak that she needed a cane to walk which she got over in months following. She took medication such as methotrexate, cyclophosphamide, carboplatin, and etoposide. This could all be immediately reversed if an afflicted Upir feeds off a Humanoid grown at the Godfrey Labs.

It should be noted that an upir's strength is the only physical ability that is not affected by the Neurotoxin, as she was shown to only be as fragile as a human, spraining herself after falling off a chair, though she still ripped out Marie Godfrey's throat and lifted Roman several feet above her head with one hand. Her immune system was shut down, physically making her weak and making her age at an accelerated rate and develop the side effects of ageing such as cancer development due to a decaying bodily system. The Upir Feeding Tanks were designed to develop Humanoids, but the project only succeeded in creating plasma and tissue supplements to fully control an upir's hunger and sustain them. A fully developed Humanoid can completely repair and enhance an Upir's self-reparation capabilities to unnatural levels to help them rejuvenate and restore themselves from damage or abnormal conditions caused by Upir Neurotoxins.

In addition, the venom was able to kill a Jarmungandr, as they are sulfur-based life form and the Upir toxin has an extremely high concentration of nitrogen oxide. Exposure to it causes a robust reaction capable of incinerating the Jarmungandr exposed to it.

Customs Edit

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The picture of a Jarmungandr, also known as Omul Negru, the Upir boogeyman

Many upirs do not live together, having normal relations of human families, as well as leaving their parents to explore their immortal lives. They also do not have any form of government for themselves and do not keep themselves in check in such a manner. Without order, upirs become scattered across the world blended into the human population. Alternatively, many upirs live in communities where other upirs are, sometimes forming a type of tribe. This tribe will often compile upirs with high-class jobs, such as historians, physicians, professors and scientists. The tribes also seem to pass news to others, as there were upir, who also knew about the Upir Virus, describing the events of the infected killing others as Upir-on-Upir violence. Some Upir are not as social as those in a tribe, and therefore, who do not or seldom socialize with others and also are not aware of any news about their kind. The upir have myths from, most prominently found from Carpathian stories. These myths are actually depictions of the Jarmungandr, known as Omul Negru to the upir. Since these creatures are seemingly older than upir, they have fallen into upir myths and legends.
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The blood spilt from Roman's slit arms forming a wing like picture after his death and during his resurrection.

Known UpirsEdit

AppearanceEdit

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In a hunger induced daydream, Roman's jaw dislocates from his skull and stretches his face as low as to his neck.

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Upirs are indistinguishable from humans. They possess an enhanced bite and jaw strength. In one instance,
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or at least in a daydream Roman had, his lower jaw dislocated, causing cracking noises in his face and his mouth extended downward as far as his neck. This made his bite so big that it engulfed the entire throat of Miranda in said daydream. In reality, upir have inhuman jaw flexibility and strength, allowing an upir to stretch their mouths while about to bite, though this is usually seen when the upir is overwhelmed with bloodlust or hunger. Roman's mouth again stretched and grew when he killed a guard at a blood bank to protect Annie. This instance was after Roman was on a blood high and overwhelmed with animalistic aggression. Roman's canine teeth briefly transformed into fangs in the first season, and this was an
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Upir's only transformation until the second season changed this, making the vampiric teeth noncanon. A flashback of Olivia's awakening as a full upir in the first season showed her with fanged canine teeth as well. While they do not truly physically change and have a perfected figure due to being full upir, they experience changes in their bodies, such as dystrophy in their muscles or even cancer in unbelievably rare cases, as well as severe dystrophy, sometimes even to the point where
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An upir's inhuman jaw flexibility

they need a cane to walk and develop wrinkles and signs of aging, is mostly an effect of an Upir Neurotoxin and can render an upir almost mortal, giving an upir a human lifespan and human vulnerabilities to aging and cancers. Olivia developed these symptoms some time after Roman drained her of blood and being an untested Upir Neurotoxin enzyme. Upir can also be impregnated by humans to have half upir children. It is unknown if upir can impregnate each other and if so, what kind of
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Pryces autopsy on an Upir infected with the Upir Virus

offspring would be produced. Half upir can impregnate humans and have quarter upirs with the possibility of developing psionic powers, like Nadia's telekinetic death stare.
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Roman after losing control of his hunger and killing a homeless man named Gaber at an abandon building. He had first asked him about his family so he could take care of them before he fed on him. Roman was distraught for what he had done.

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{Click to Animate} Roman attacks Olivia and kills her, with her consent

Powers & AbilitiesEdit

Enhanced Strength

Click For Animation Roman, weakened by his human transference treatments is easily overpowered by Olivia.

Full upirs, however, have abilities that are not possessed by half upirs. A full upir's healing and durability are strengthened by their diet and their recovery ability can be taken away for months if they lose vast amounts of blood.

Full Upir Edit

  • Enhanced Strength - Upirs are arguably the strongest beings in the series or are equal in strength to vargulves or reanimated being, as they have overpowered, beaten, incapacitated, mutilated, and killed humans with inhuman ease. Upirs have been known to be more than capable of overpowering and easily able to kill humans bare-handedly, usually either through tearing of body parts and mutilating them or bending and breaking their bodies in lethal ways, though such
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    Clementine Chasseur after being skinned alive by Olivia, possibly bare-handedly

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In the first season, Roman briefly transformed his canine teeth into fangs.

unnatural feats are only possible with slightly greater physical effort, while an upir could simply strike a human in the face with an open hand. Upirs are strong enough to bludgeon someone to death with their bare hands, though another upir will not die from it. At their best effort, an upir could easily send humans flying into the air 20 or more feet in the air. This also applies to Johann Pryce's, a human with constant hysterical strength, fear of Olivia Godfrey for her strength and when he was casually grabbed by the neck and forcibly pinned 
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Marie Godfrey after being killed by having her neck ripped open by Olivia

against the wall by Roman, a full upir, who had been similarly overpowered by Pryce when he was still only a half Upir. A full upir can lift uplift and rend a transformed werewolf or vargulf with little effort, such as when Roman did this to Peter's wolf body to pull him out of it. It would appear that the strength
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Annie bludgeoning an Upirs head with her fist

required to lift others off the ground and sending them flying into the air needs at least some effort for Roman did not always do so when fighting against cultists and needed some more momentum to use the peak of his strength and send them flying into the air, as he would sometimes just grapple with them and overpower them in a second. He could pin people down with no effort and great ease, but with enough effort, he could rip apart flesh and send people flying at the
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Roman choking a man with a metal grip

speed of a moving car. Olivia used enough force to stun a man in the 1400's by elbowing him in the torso and
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Roman knocks a man unconscious with a slap to the forehead

knock him to the ground. It is assumed Roman would have been able to fight Olivia on equal grounds before he was in the process of trying to exchange his tissue, blood and organs for that of humans to become human. It is possible that reanimated beings such as Shelley can be equal in strength to a full upir or even surpass them in strength. Olivia was briefly held in a choke hold by Norman when he tried to kill her, though she then got the upper hand when she broke out of her surprised state and broke his arm and tore out his heart. Other upir are shown to have strikes with equal force and damage to a hammer, allowing an upir to bludgeon a human or another upir with their fists. Also, upirs can dig through flesh in a similar way of digging through sand or dirt, which allows them to shred the flesh of a human or upir with their fingers. The Upir Virus seemingly causes an upir to be able to overpower, shove, and shred through their own kind with little to no effort.
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With enough effort, Roman can pull flesh apart. He used this to stop Peter when he finally succumb to his vargulf condition

  • Heightened Senses - When having a hunger attack, which makes their vision hazy and their sight to be only on living creatures. They can hear the heartbeat of a human from a few feet away and can clearly see their veins and blood vessels in their necks and skin. Their senses seem primed to sense their prey and their food as Roman had not been seen sensing anything other than people's hearts. Olivia was unable to sense the bird that flew into a window, though this was probably because the only way to enhance their senses is to be overwhelmed by hunger.
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  • Regenerative Healing - Like all other abilities possessed by full upir, healing and all forms of physical recovery are greatly enhanced. Upir have the ability to physical recover from trauma in one or more hours with little to no medical treatment. This allows an upir to be able to make a rapid and full recovery from any form of injury except decapitation, severe mutilations, especially to the heart, head or brain, or cremation. Trauma seems to daze upir, as Olivia was half conscious and was tired after being shot in the heart by Clementine Chasseur. Marks in the place of self-inflicted mortal wounds that made turned a half upir into a full upir will appear when an upir transforms, leaving them healed. The scars of physical trauma, if any, that was used to make them full Upirs seem to remain, as Olivia still has a scar on the small on her back and her tail like deformity had been before she cut it off and bled to death. Roman awoke minutes after slicing his forearms down to the tendons and bleeding to death, with only scars were the wounds had been. The scars seem to have disappeared or have faded. Desiccation and some chemicals can stunt their healing. Olivia's rehabilitation made it so that her tongue did not heal immediately. She also cut herself while shaving her legs and it did not heal immediately, though she stated that it would heal soon, probably in an hour or more. Being struck in the heart while it being drained of blood and tissue pieces could kill an upir as Destiny killed one infected with the Upir Virus with the use of a body cavity vacuum inside a mortuary, a device that is used to liquefying, grinding, and shredding tissues and organs, as well as vacuum them out of the body. Therefore, liquidating or heavily mutilating an upir, especially on the inside, can kill them. At the same time, vacuuming out or removing tissues and organs such as the brain or heart, or simply grinding or shredding them, can kill upirs as well. Permanent damage can, in fact, be dealt to an upir, though it may not be fatal. Roman was at the risk of being made permanently deaf when a syringe was near a tube connected to the inside of his hearing organs. Unfortunately, if the upir is attacked with similar strength to their own, they will be far more vulnerable to the trauma as Roman suffered a seizure after and gained a concussion when attacked by a creature stronger than himself.  Permanent damage can, in fact, be dealt to an upir, though it may not be fatal. Roman was at the risk of being made permanently deaf when a syringe was near a tube connected to the inside of his hearing organs.
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    An Upir ripping out the chest of another and mauling him to death

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    Romans vision blurred by his hunger

  • Enhanced Durability - Upir skin is strong enough to impervious to glass and anything as sharp as it. This can also mean they are immune to great physical trauma caused by such things as falling on hard stone. Roman was struck with a metal pole at full force, and it did nothing as if it were hitting metal. This was while Roman was feeding on a homeless man named Gaber. Roman then choked the man that hit him in the back, making cracking noises from his neck. Other than that, the upir can survive and recover any injury done to them, even if they do not heal from it fully, though only dismemberment of the head, brain, or heart, as well as cremation, can truly kill them.
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    Roman being struck in the back and not reacting at all

  • Mesmerization - All upirs, half or full, have the ability to mesmerise people and gain full control of their minds, actions, and overall perception of reality by simply looking at a person's eyes. It is shown that full upir are capable of using this ability on half upir, as Olivia used it on Roman to have him impregnate Letha Godfrey. It is only known that vargulfs are not susceptible to memorization while transformed, but it remains unknown if this is the case for regular werewolves or when werewolves are in human form. Upir can even mesmerise themselves using looking at their reflections eyes, such as Roman made himself see Shelley in visions, much like his catabasis, which also seemed to be some form of self-inflicted mesmerization to put the pieces of a metaphysical puzzle together and defeat his inner demons. That was only when he was a half upir.
  • Immortality - An upir can live forever until they are killed by one of their weaknesses. They mature at a certain age and then stop ageing because they are immune to all disease.

Half UpirEdit

  • Superhuman Strength- Roman was shown to be strong enough to fend off a transformed vargulf with an axe handle, which she then threw away. He was easily overpowered by Johann Pryce when he was half upir, showing his limitations. Also, the elderly Magdalena, who was seemingly half upir at the time and then mesmerized by an Upir Nazi, was able to almost rip the throat out of Nicolae, his running away being the only thing that saved him from death.
  • Regenerative Healing - Half upirs appear to heal faster than humans. This is demonstrated by Roman, as he left several cuts on his body that were gone after a while. Although, half upir, while not requiring medicine, Roman did place bandages over the cut on his face. Also he felt no pain from cuts, probably due to having cocaine in his system at the time, and was perfectly healthy throughout his life despite having consumed several drugs and heavy smoking, and possibly was likely to be at risk of second hand smoking, as Olivia was also a heavy smoker.
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    Half upir, Roman, mesmerizing a man

  • Mesmerization - All upirs have the ability to mesmerise people, though half upirs suffer nosebleeds and severe head pain, which according to Roman, is worse than being hit by a bus.
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Olivia's feeding ground in the abandoned Godfrey Mill

FeedingEdit

While upirs can consume regular food and drink, as well as drugs and alcohol, without any side effects, these creatures are reliant on human
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An gouging Upir bite wound

or synthetic tissue and blood of any living creature, to satisfy their urges, they will weaken and become rabid without enough. This rabid hunger is similar to substance addiction and contains withdrawal symptoms, with both symptoms of addiction and withdrawal becoming worse every day of the upir's life. They most often can get blood from raw meat or bone marrow or simply directly from the source as seen by both Olivia and Roman. Upir seemingly need to adjust to their new diet of blood and raw tissue and, while adjusting, their bodies will seemingly reject the blood and cause the upir to vomit it out, and sometimes become slightly
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Roman feeding excessively on the supplement of the upir Feeding Tank before becoming sick.

feverish and develop mood swings and all other drug withdrawal type symptoms, as blood to them is like a drug in their system. They prefer their food uncooked as cooked food is not satisfying to them. This also applies to any form of sustenance they may use, whether synthetic or organic, as when Roman is trying to consume from an Upir Feeding Tank, vomited the food back out and became sick and violent for hours after. Olivia's first treatment caused her to almost fracture Pryce's skull, and he begged her not to kill him, which she obliged to. Their bodies mostly prefer to have blood from living sources and not preserved, as preserved, or synthetic
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Roman close to losing control of his hunger when in front of a human.

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Roman eating off a pimp named Davy when he still had the willpower to not kill his victims by feeding on them to the point of mortal damage

 food sources can cause the body to reject it, or it may not give as much nutrition as living sources do as no matter how much preserved flesh and blood Roman consumed he could not control his urges fully. This is because an upir's hunger grows more insatiable and unstable with each day of its immortal life causing them to lose control and go into something similar to feeding frenzies and feed until they can control themselves again, usually after violently feeding on and killing live creatures, especially humans. This lack of self-control is the reason that some upir were caught and killed by humans in the past. Roman eventually
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Roman choking someone as strong a Pryce

killed humans when he fed on them as he did not before and also started feeding on other living creatures like animals, just as Olivia fed on horses owned by her late husband and covered it up by saying she had them killed in the grief of the loss of her husband to not arouse suspicion. Roman also could not control his desire to feed, as he also had daydreams or dreams of feeding. He also occasionally feeds off living creatures, such as a prized horse he owned, as well as drifters, degenerates, drug addicts, criminals, thugs and homeless people that he knew that people would not miss. This was the same with Olivia when her supplement was not available and most upir who choose to hunt and kill humans. Eventually, he fed in a way that
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Olivia after killing Priscilla, digesting the contents of her chemical system to rejuvenate her own bodily system and heal her cancers and semi mortality.

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Roman's slight lack in morality by sometimes thinking of people as food and thinking of blood types as flavor

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Roman when finally becoming unable to feed without killing

killed people, as his hunger was insatiable. His hunger caused him great emotional stress whenever he had an intense hunger attack or attacked someone. He cried and wept whenever he lost control, of his hunger as he wanted to do not harm. Upir have been notorious for their feeding and failing to control their hunger, as they lose control in a way that kills several people. Eventually, the deaths that occur can be traced to them, forcing them away for fear that they will be killed by humans, especially those who know of their existence and will hunt them down. Olivia saved herself and Roman from such a fate, she married J R Godfrey to establish the scientific research to allow them to control their thirst, which eventuality resulted in the development of the Upir Feeding Tank The supplement of the feeding tank could cause associative euphoria, making Olivia think that she had explained herself fully to Roman and that Roman loved her deeply the first time she fed on it, unlike Roman, who completely rejected it the first time he tried it and it made him sickly for an hour as his
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Upir nutrient seen for the first time

metabolism was not used to the supplement. Also, Olivia almost fractured Pryce's skull do to a violent reaction to the supplement. Before the Feeding Tank was developed, Olivia fed at the Godfrey Mill by feeding on its transients and left several blood paintings in it, even one of a phoenix creature. She was afraid when Roman, Peter and others were at the Mill, as they were on her hunting grounds. The upir Feeding Tanks was designed to develop Humanoids, but the project only succeeded in creating plasma discard and tissue supplements to better control an upir's cravings and instinctual aggression. In a way, these were failed experiments that were being fed to Olivia. A fully developed humanoid can completely repair and enhance an upir's self-repairing capabilities to great levels to rejuvenate them from damage and abnormal conditions, like those caused by the upir neurotoxins used in Olivia's treatments.

Upirs like Annie, who have lived throughout the centuries past the Dark Ages and resist the urge to butcher, and kill humans for blood, have usually found jobs that keep them close to sources of blood, such as the doctors, nurses, lab technicians, morticians, and EMT's. Others have become historians, professors and scientists. According to Annie, half the morticians in America are upir. These upirs will work in the medical field, and therefore in the Emergency Room or even a medic in the military. Annie herself has worked as a military nurse in many wars throughout her time as a full upir. To Annie, this path was similar to animals living in the wild and fitting into their habitat. Commonly, upirs will usually pass off as being higher class citizens in their communities. These tribes often assist each other's struggles, especially with violent feeding, while also have friendly gatherings, sometimes with blood-based meals, one of these is Blood Pudding.

It is said that upirs that feed on other upirs can become horribly sick, though Roman was able to drain Olivia without any seen symptoms. Although, it is possible that this sickness is not immediate and takes some time
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Blood Pudding, an meal commonly shared by Upirs living in the same community

to manifest itself. Alternatively, the Upir Virus causes the infected upir to become unable to feed on blood unless it is from another upir. In fact, the infected become rabid and mindlessly hunt for their own kind, seeing their own kind as outlined in a red aura. They will stalk their prey animalistically before butchering them to death. This virus causes an upir to lose their minds, reducing them to mindless animals that only know to hunt and kill their own kind.
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Olivia after feeding at the Mill

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Roman imagines himself feeding off of Miranda and being covered in blood

PsychologyEdit

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Roman about to kill a Caul member

Upirs are predatory creatures and are far more brutal than their human appearance suggest. Although they can control themselves in a sophisticated and human manner, duress reduces them to a more feral state. This also applies their desire for blood. The longer they abstain from blood, the less in control of themselves they will be, leading to the high possibility of attacking and killing any human they are near. Upirs are capable of human emotions, such as compassion, love, and self-control. However, often with age the older, they get, the less intense these emotions become. Upirs at any stage will struggle with humanity at some point in their lives, as Roman constantly did. Since they are living creatures, they have working brains with active nerves, allowing certain drugs that would be administered to reanimated upirs, can affect the brain and, therefore, change their emotions, but only when they are rehabilitating from dying or are recovering from a combination of
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Roman looking at a video of a surgery that causes a hunger attack for him

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Roman using his bite as a weapon in battle

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Roman after eating off of a pimp named Davy to avoid eating a prostitute he liked. This was when he still had the ability to feed without killing his victims.

blood loss, trauma and a coma. This only seems to work if the upir is under the effects of blood loss as Olivia was vulnerable to the side effects of her treatments during her recovery after her death at Roman's hands and Roman was drugged by Dr Galina and was dazed. An upirs hunger can cause them great emotional stress whenever they had a strong hunger attack, consisting of hazed senses and being overwhelmed by sensing a great quantity of blood and flesh. Roman saw a video of surgery that triggered a hunger attack. This hunger attack included hazy and blurred vision and senses. It also caused an upir to lose their temper easily, constantly become, impatient, jittery, agitated, angry, or even violent. Roman yelled at everyone at his workplace and threw an electronic tablet to the floor when the blueprints of Pryce's secret lab was not found when he wanted it. He took his anger out on anyone he saw calling them useless to him. Roman cried and had breakdowns whenever he lost control of his hunger as he wanted to do not harm anyone. If threatened, upirs usually become more prone to manic, instinctual aggression. Olivia was told by Norman that he was going to watch her die horribly from her cancer and even had a knife to weaken her long enough to be killed, making her hate him and go back on her good and loving personality to her more savage and cruel one, killing her daughters new body, Prycylla to cure herself and then ripping out Norman's heart to make him suffer.
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A half upir Roman shows no pain to the self-inflicted cut through his chest

AgingEdit

Upirs are immortal, and do not physically age, remaining identical after reaching maturity in the discovery of their powers this may happen at differing ages, for instance, Roman reached full upir status at 18; in Olivia's case it happened when she was noticeably younger. Upir do not seem to age a day from the day they died and arose as the immortal creatures they become once they die, though their death must be at their own hand. But if they do age, they would stop aging when they reach their physical prime, as Olivia was a teen upon turning into a Full upir and now has the appearance of a woman in her 30's.

WeaknessesEdit

  • Decapitation - Separating an upir's head from the rest of the body will result in its death and is one of
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    Annie uses flammable gas to burn herself to death

    the common ways to kill them. Severe damage to the brain may also be fatal.
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  • Cremation - Cremation is the second best way to kill an upir that gets rid of any evidences that it existed.
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Roman suffering a concussion and seizure after his head is bashed by another Upir's strength

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    Physical Trauma - While it is usually not fatal, trauma and damage to the body can actually cause some harm to an upir, though usually by causing pain or slight weakness, such as when Olivia was shot in the heart or when she cut herself, feeling pain. Also, an upir has the same weak points as a human being and can be affected by strikes and impacts. Enough force can even break through their enhanced resilience and cause greater harm, as Roman suffered a concussion and seizure when his head was bashed against a wall by another upir. This caused him to require more recovery time than normal. Being struck in the heart while it being drained of blood and tissue pieces could kill an upir as Destiny killed one infected with the Upir Virus with the use of a body cavity vacuum inside a mortuary, a device that is used to liquefying, grinding, and shredding tissues and organs, as well as vacuum them out of the body. Therefore, liquidating or heavily mutilating an upir, especially on the inside, can kill them. At the same time, vacuuming out or removing tissues and organs such as the brain or heart, or simply grinding or shredding them, can kill upir as well. Permanent damage can, in fact, be dealt to an upir, though it may not be fatal. Roman was at the risk of being made permanently deaf when a syringe was near a tube connected to the inside of his hearing organs. Even then, only heavy mutilation or removal of the head, brain or heart, will truly kill an upir. Roman also experienced the weaknesses of broken bones after being tackled out his window and falling on the ground with the impact breaking his body and leaving him vulnerable to Peter's vargulf. He seemed to think it was permanent as he asked Peter not leave him in such a state and to kill him instead.
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    Heart Piercing - A direct strike to the heart cannot kill an upir, however, it can weaken them long enough for them to be killed, so maybe an hour or less. Anticoagulants are seemingly capable of making the weakened period longer. The way to pierce their hearts is to aim under the sternum then twist upwards and towards the spine. Also, if the heart is destroyed, it can be fatal to an upir. Being struck in the heart while it being drained of blood and tissue pieces could kill an Upir as
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    Destiny killed one infected with the Upir Virus with the use of a body cavity vacuum inside a mortuary, a device that is used to liquefying and shredding tissues and organs, as well as vacuum them out of the body.
  • Heart Removal - If their heart is extracted from their bodies or their chest is ripped out, an upir will die in a similar way that they die from decapitation.
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    Roman killed by his throat and heart being ripped out by Peter's vargulf.

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    A slain Upir

  • Suffocation - It is believed that, much as Olivia became comatose and seemingly died after her attack by Roman, suffocation, either of the lungs or the blood vessels or body parts or systems can cause the same effect. Pryce's and Olivia's plan to copy her mind unto another upir and leave her own body
dead, as it was infected with the Upir Virus, involved seemingly killing, or at least making Olivia's real body seem dead, with a morphine overdose. It is implied that removing the lungs has a high possibility of killing an upir, though it may just cause them pain, as they are said to survive any damage other than severe damage, destruction or removal of the heart, brain, or head. Olivia was seemingly choking to death when Shelley was strangling her. 
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Olivia seemingly comes close to death when being choked by Shelley.

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Roman being unable to hold Andreas's body on his own while having super human strength

  • Normal Stamina - Upirs, while also have the same weak points as a human being, also cannot always sustain prolonged physical or mental effort, unless they are feeding or on a blood high. This can limits their physical strength, as those who do not feed as often or from the right source can lose their enhanced resilience while they can still recover from any injury without complication or medicinal help regardless. Both trauma and damage can have the same painful, weakening, disorienting, or stunning effect on an upir as it does on normal humans, though this usually is for those who do not feed regularly or the right amount. Permanent damage can, in fact, be dealt to an upir, though it may not be fatal. Roman was at the risk of being made permanently deaf when a syringe was near a tube connected to the inside of his hearing organs.
  • Hunger - Being deprived of blood and/or flesh not only causes an upir to weaken but also to lose their ability to control their hunger and sometimes attack humans to feed on them. Theirs grows with every day they live until they attack everything with blood and flesh uncontrollably. They soon will kill while feeding and lose their humanity to their hunger and lose all self-control. The upir Feeding Tank can successful curb an upir's appetite and stop their loss of control and a full grow humanoid from the lab and be fed on to help heal an upir if they develop unnatural conditions.
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    Roman tempted by an open wound

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Olivia's tongue after it being sowed back on, thought it still needed stitches on

  • Blood-Loss - Without feeding on enough blood and flesh, upirs can be rendered almost mortal and be vulnerable to long term effects of damage that feeding cannot heal immediately and require, such as when Olivia had loss of speech, was in a coma for almost a year, and had severe muscular dystrophy after being drained of blood by Roman, which caused her to become so weak that she needed a cane to walk. This did not hinder her superhuman strength as she ripped open Marie Godfrey's neck, either with her bare
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    Destiny kills an Upir infected with the Upir Virus by stabbing it in the torso with a blood cavity vacuum at the mortuary, effectively vacuuming its blood and some internal tissues out

    hands or with her bite. Roman lost his enhanced strength and resilience due to his treatments, as seen when he fought a cultist with a knife and was slices in the arm and had to dodge attacks.
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Nate, an Upir, being mauled to death by another infected by the Upir Virus

He was once durable enough to take a direct strike to the back with a metal pole, and it is landing on him as if he were made of metal. His strength was also lessened as he needed a shovel in combat to win in a fight against cultists and to beat the cultist he fought to the floor before smashing the blade against the cultists head. The cultist was not even killed by this, even while Roman was seemingly fully exerting his strength. It is implied that he could have been able to fight his mother on equal grounds if he were not taking the treatments but this was not demonstrated. Being struck in the heart while it being drained of blood and tissue pieces could kill an upir as Destiny killed one infected with the Upir Virus with the use of a body cavity vacuum inside a mortuary, a device that is used to liquefying, grinding, and shredding tissues and organs, as well as vacuum them out of the body. Therefore, liquidating or heavily mutilitating an upir, especially to the heart, brain or head, can kill them. At the same time, vacuuming out or removing tissues and organs such as the brain or heart, or simply grinding or shredding them, can kill upir as well.
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    Olivia being drained of blood and left to fall into a coma by Roman

    Upir Neurotoxin: An enzyme derived from an upir's own body can be used for medicinal purposes, breaking down the immune system and weakening an upir's cellular defences to allow for further treatments. It was used in Olivia's recovery after being killed by Roman, as she could not recover on her own. It also caused her to become more human, giving her tissue dystrophy, chemically enhanced emotions and empathy, which was hard to overcome, accelerated ageing and decay and even human-like vulnerability to cancers, which is a possible side effect of the accelerated ageing. Olivia had severe muscular dystrophy after being drained of blood by Roman and being given the Neurotoxin in her treatments, all of which caused her to become so weak that she needed a cane to walk which she got over in months. She took medication such as methotrexate, cyclophosphamide, carboplatin, and etoposide. This could all be immediately reversed if an afflicted upir feeds off a Humanoid grown at the Godfrey Labs. It should be noted that an upirs strength is the only physical ability that is not affected by the Neurotoxin, as she was shown to only be as fragile as a human, spraining herself after falling off a chair, though she still ripped out Marie Godfrey's throat and lifted Roman several feet above her head with one hand. Her immune system was shut down, physically making her weak and making her age at an accelerated rate and develop the side effects of ageing such as cancer development due to a decaying bodily system. The Upir Feeding Tanks was designed to develop Humanoids, but the project only succeeded in creating plasma and tissue supplements to fully control an upir's hunger and sustain them. A fully developed Humanoid can completely repair, and an enhance upir's self-reparation capabilities to unnatural levels to help them rejuvenate and restore themselves from damage or abnormal conditions caused by upir Neurotoxins.
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    Pryce sedates an Upir scientist from behind

    Pryce's Sedative: Pryce used a sedative on Roman as a half upir that left him comatose for days. He then used it on a human male that he copied his consciousness onto. The sedative then was shown to be able to render full upir unconscious for an hour or more, as Pryce used it to copy Olivia's consciousness onto.
  • Hemophilia Serum: Developed by the Godfrey Institute, this enzyme inhibitor is meant to cause acute hemophilia, preventing clotting factors and inducing excessive bleeding. The effect of it on a living organism was said to be "Like an atom bomb going off in the bloodstream". It would weaken or potentially almost cripple an upir long enough for them to be killed. If an upir who is going through Pryce's cure treatments is subjected to the serum, it may kill them.
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An IV line with the Hemophilia Serum

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    Roman heavily weakened by bullets laced with Heparin

    Anticoagulant: Drugs like Heparin, can be placed on the weapon that pierces their hearts and further its effectiveness at weakening them, as their blood will be unable to clot and therefore weakening their damage reparation abilities and physical recovery. With that, they are physically react to wounds like any
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    Protamine sulfate being used to cure Roman of the Heparin that is severely weakening him

    human would, though they have minutes before succumbing to these weaknesses, allowing them to use their strength to fight back. Not even feeding can stop the symptoms of the anticoagulant. An injection of protamine sulfate, a clotting agent injected into the neck, can reverse the effects of the anticoagulant as fast as the anticoagulant takes to weaken the upir.
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    Olivia's decayed body caused by the Upir Virus

    Rare Cases: Upirs can also become sick with diseases such as congenital heart disease, which can occur naturally, along with vulnerability to cancers and the Upir Virus. While they are the only species to be vulnerable to this infection, cancers happen to most upir whose immune system is broken down by upir Neurotoxin. It is possible that if such a disease is inside the upir before they become full upir, it might survive their suicide and possibly be able to still harm them.

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